Previous Malignancy as a Risk Factor for the Second Solid Cancer in a Cohort of Nuclear Workers

This paper describes the results of epidemiological analysis a cohort nuclear workers hired at main facilities “Mayak” Production Association located in city Ozyorsk Southern Urals Russian Federation. Previous malignancy as risk factor for second cancer 22,373 occupationally exposed to ionizing radiation has been analyzed retrospective study with more than 60 years follow-up. Information on and non-radiation factors (attained age, sex, tobacco smoking), well dose exposure occupational obtained using data from register other population registries created Epidemiological Laboratory Biophysics Institute. Poisson’s regression realized “Amfit” module “Epicure” statistical package applied analysis. Excess relative per 1 Gy absorbed external gamma internal alpha calculated linear model. Among 2,471 cases accumulated end follow-up 6.4% have diagnosed among protracted gamma- radiation. The (except non-melanoma skin cancer) previously was about 4 times higher after decade compared those patients who had single only. showed that previous along is statistically significant carcinogenic Doi: 10.28991/SciMedJ-2021-0301-2 Full Text: PDF